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Cellosaurus CHOmt17-0 (CVCL_YY02)

[Text version]
Cell line name CHOmt17-0
Accession CVCL_YY02
Resource Identification Initiative To cite this cell line use: CHOmt17-0 (RRID:CVCL_YY02)
Comments Characteristics: Can produce a considerably large amount of sialyled glycoproteins.
Selected for resistance to: ChEBI; CHEBI_44185; Methotrexate (MTX).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:10860; ST6GAL1.
Genetic integration: Method=Transfection; Gene=MGI; MGI:1354951; Gne.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCIt; C129640; Cobalt-60 gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Homozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_7180 (CHO-DG44)
Children:
CVCL_YY03 (CHOmt17-100)CVCL_YY04 (CHOmt17-200)CVCL_YY05 (CHOmt17-300)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=29439861; DOI=10.1016/j.jbiosc.2018.01.010
Nguyen T.S., Misaki R., Ohashi T., Fujiyama K.
Enhancement of glycosylation by stable co-expression of two sialylation-related enzymes on Chinese hamster ovary cells.
J. Biosci. Bioeng. 126:102-110(2018)

PubMed=32125558; DOI=10.1007/s10616-020-00381-z; PMCID=PMC7225233
Nguyen T.S., Misaki R., Ohashi T., Fujiyama K.
Enhancement of sialylation in rIgG in glyco-engineered Chinese hamster ovary cells.
Cytotechnology 72:343-355(2020)

Cross-references
Encyclopedic resources Wikidata; Q98125622
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number7