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Cellosaurus NDi001-A (CVCL_YN03)

[Text version]
Cell line name NDi001-A
Synonyms HL-60-iPSC c25; HL-60 iPSC c25
Accession CVCL_YN03
Resource Identification Initiative To cite this cell line use: NDi001-A (RRID:CVCL_YN03)
Comments From: University of Notre Dame; Notre Dame; USA.
Population: Caucasian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 36Y
Category Induced pluripotent stem cell
Publications

PubMed=33370871; DOI=10.1016/j.scr.2020.102096; PMCID=PMC8031422
Yamasaki A.E., Warshaw J.N., Kyalwazi B.L., Matsui H., Jepsen K., Panopoulos A.D.
An iPSC line derived from a human acute myeloid leukemia cell line (HL-60-iPSC) retains leukemic abnormalities and displays myeloid differentiation defects.
Stem Cell Res. 49:102096-102096(2020)

Cross-references
Cell line databases/resources hPSCreg; NDi001-A
Encyclopedic resources Wikidata; Q98127502
Entry history
Entry creation12-Mar-2020
Last entry update19-Dec-2024
Version number9