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Cellosaurus HEC-1BE (CVCL_YJ46)

[Text version]
Cell line name HEC-1BE
Synonyms HEC1BE
Accession CVCL_YJ46
Resource Identification Initiative To cite this cell line use: HEC-1BE (RRID:CVCL_YJ46)
Comments Population: Japanese.
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7329; MSH6; Simple; c.4001+1G>T; ClinVar=VCV001736936; Zygosity=Heterozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; 9122; PMS2; Simple; p.Arg802Ter (c.2404C>T); ClinVar=VCV000009237; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (PubMed=15901131).
Disease Endometrial adenocarcinoma (NCIt: C7359)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0294 (HEC-1-B)
Sex of cell Female
Age at sampling 71Y
Category Cancer cell line
Publications

PubMed=8847459
Okamura N., Mori Y., Endo T., Ito E., Kudo R.
Experimental studies on the cell adhesion molecule E-cadherin and in vitro invasion of endometrial carcinoma cell lines.
Nihon Sanka Fujinka Gakkai Zasshi 48:335-342(1996)

PubMed=12893190; DOI=10.1016/S0090-8258(03)00335-4
Tanaka R., Saito T., Ashihara K., Nishimura M., Mizumoto H., Kudo R.
Three-dimensional coculture of endometrial cancer cells and fibroblasts in human placenta derived collagen sponges and expression matrix metalloproteinases in these cells.
Gynecol. Oncol. 90:297-304(2003)

PubMed=15901131; DOI=10.1016/j.prp.2005.01.002
Murai Y., Hayashi S., Takahashi H., Tsuneyama K., Takano Y.
Correlation between DNA alterations and p53 and p16 protein expression in cancer cell lines.
Pathol. Res. Pract. 201:109-115(2005)

Cross-references
Cell line databases/resources cancercelllines; CVCL_YJ46
Encyclopedic resources Wikidata; Q94091657
Entry history
Entry creation19-Dec-2019
Last entry update05-Oct-2023
Version number8