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Cell line name |
HEC-1BE |
Synonyms |
HEC1BE |
Accession |
CVCL_YJ46 |
Resource Identification Initiative |
To cite this cell line use: HEC-1BE (RRID:CVCL_YJ46) |
Comments |
Population: Japanese. Derived from site: In situ; Endometrium; UBERON=UBERON_0001295. |
Sequence variations |
- Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 7329; MSH6; Simple; c.4001+1G>T; ClinVar=VCV001736936; Zygosity=Heterozygous; Note=Splice donor mutation (from parent cell line).
- Mutation; HGNC; 9122; PMS2; Simple; p.Arg802Ter (c.2404C>T); ClinVar=VCV000009237; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (PubMed=15901131).
|
Disease |
Endometrial adenocarcinoma (NCIt: C7359) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_0294 (HEC-1-B) |
Sex of cell |
Female |
Age at sampling |
71Y |
Category |
Cancer cell line |
Publications | PubMed=8847459 Okamura N., Mori Y., Endo T., Ito E., Kudo R. Experimental studies on the cell adhesion molecule E-cadherin and in vitro invasion of endometrial carcinoma cell lines. Nihon Sanka Fujinka Gakkai Zasshi 48:335-342(1996) PubMed=12893190; DOI=10.1016/S0090-8258(03)00335-4 Tanaka R., Saito T., Ashihara K., Nishimura M., Mizumoto H., Kudo R. Three-dimensional coculture of endometrial cancer cells and fibroblasts in human placenta derived collagen sponges and expression matrix metalloproteinases in these cells. Gynecol. Oncol. 90:297-304(2003) PubMed=15901131; DOI=10.1016/j.prp.2005.01.002 Murai Y., Hayashi S., Takahashi H., Tsuneyama K., Takano Y. Correlation between DNA alterations and p53 and p16 protein expression in cancer cell lines. Pathol. Res. Pract. 201:109-115(2005) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_YJ46
|
Encyclopedic resources |
Wikidata; Q94091657
|
Entry history |
Entry creation | 19-Dec-2019 |
Last entry update | 05-Oct-2023 |
Version number | 8 |
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