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Cellosaurus EndoC-betaH1 SLC30A8-KO (CVCL_YB10)

[Text version]
Cell line name EndoC-betaH1 SLC30A8-KO
Accession CVCL_YB10
Resource Identification Initiative To cite this cell line use: EndoC-betaH1 SLC30A8-KO (RRID:CVCL_YB10)
Comments Virology: Contains an integrated xenotropic MuLV-related virus (XMRV) Bxv-1 (from parent cell line).
Knockout cell: Method=CRISPR/Cas9n; HGNC; HGNC:20303; SLC30A8.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Pancreatic beta cell; CL=CL_0000169.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_L909 (EndoC-betaH1)
Sex of cell Female
Age at sampling 7-11FW
Category Transformed cell line
Publications

PubMed=31976379; DOI=10.12688/wellcomeopenres.15447.2; PMCID=PMC6961417
Grotz A.K., Abaitua F., Navarro-Guerrero E., Hastoy B., Ebner D., Gloyn A.L.
A CRISPR/Cas9 genome editing pipeline in the EndoC-betaH1 cell line to study genes implicated in beta cell function.
Wellcome Open Res. 4:150-150(2019)

Cross-references
Encyclopedic resources Wikidata; Q93540663
Entry history
Entry creation19-Dec-2019
Last entry update19-Dec-2024
Version number9