• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Unspecified (PubMed=23613873).
  

PubMed=23613873; DOI=10.1371/journal.pone.0061555; PMCID=PMC3629194
Martens-de Kemp S.R., Dalm S.U., Wijnolts F.M.J., Brink A., Honeywell R.J., Peters G.J., Braakhuis B.J.M., Brakenhoff R.H.
DNA-bound platinum is the major determinant of cisplatin sensitivity in head and neck squamous carcinoma cells.
PLoS ONE 8:E61555-E61555(2013)

PubMed=26122845; DOI=10.1158/0008-5472.CAN-15-0528
Stoepker C., Ameziane N., van der Lelij P., Kooi I.E., Oostra A.B., Rooimans M.A., van Mil S.E., Brink A., Dietrich R., Balk J.A., Ylstra B., Joenje H., Feller S.M., Brakenhoff R.H.
Defects in the Fanconi anemia pathway and chromatid cohesion in head and neck cancer.
Cancer Res. 75:3543-3553(2015)

PubMed=26423134; DOI=10.1038/ncomms9399; PMCID=PMC4600715
de Lange J., Faramarz A., Oostra A.B., de Menezes R.X., van der Meulen I.H., Rooimans M.A., Rockx D.A.P., Brakenhoff R.H., van Beusechem V.W., King R.W., de Winter J.P., Wolthuis R.M.F.
Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function.
Nat. Commun. 6:8399.1-8399.12(2015)