ID   VU-SCC-9917
AC   CVCL_XX24
DR   cancercelllines; CVCL_XX24
DR   Wikidata; Q98134592
RX   PubMed=23613873;
RX   PubMed=26122845;
RX   PubMed=26423134;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Unspecified (PubMed=23613873).
DI   NCIt; C4833; Oral cavity squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   62Y
CA   Cancer cell line
DT   Created: 19-12-19; Last updated: 19-12-24; Version: 8
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RX   PubMed=23613873; DOI=10.1371/journal.pone.0061555; PMCID=PMC3629194;
RA   Martens-de Kemp S.R., Dalm S.U., Wijnolts F.M.J., Brink A.,
RA   Honeywell R.J., Peters G.J., Braakhuis B.J.M., Brakenhoff R.H.;
RT   "DNA-bound platinum is the major determinant of cisplatin sensitivity
RT   in head and neck squamous carcinoma cells.";
RL   PLoS ONE 8:E61555-E61555(2013).
//
RX   PubMed=26122845; DOI=10.1158/0008-5472.CAN-15-0528;
RA   Stoepker C., Ameziane N., van der Lelij P., Kooi I.E., Oostra A.B.,
RA   Rooimans M.A., van Mil S.E., Brink A., Dietrich R., Balk J.A.,
RA   Ylstra B., Joenje H., Feller S.M., Brakenhoff R.H.;
RT   "Defects in the Fanconi anemia pathway and chromatid cohesion in head
RT   and neck cancer.";
RL   Cancer Res. 75:3543-3553(2015).
//
RX   PubMed=26423134; DOI=10.1038/ncomms9399; PMCID=PMC4600715;
RA   de Lange J., Faramarz A., Oostra A.B., de Menezes R.X.,
RA   van der Meulen I.H., Rooimans M.A., Rockx D.A.P., Brakenhoff R.H.,
RA   van Beusechem V.W., King R.W., de Winter J.P., Wolthuis R.M.F.;
RT   "Defective sister chromatid cohesion is synthetically lethal with
RT   impaired APC/C function.";
RL   Nat. Commun. 6:8399.1-8399.12(2015).
//