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Cellosaurus IMSUTi002-A-1 (CVCL_XI77)

[Text version]
Cell line name IMSUTi002-A-1
Synonyms 7F3955-ETV6-RUNX1; CRIEPIi003-A-1
Accession CVCL_XI77
Resource Identification Initiative To cite this cell line use: IMSUTi002-A-1 (RRID:CVCL_XI77)
Comments From: Sustainable System Research Laboratory, Central Research Institute of Electric Power Industry (CRIEPI); Chiba; Japan.
Population: Japanese.
Characteristics: Transfected with a Tet-on system so as to induce the expression of a mCherry and the ETV6-RUNX fusion protein with the addition of doxycycline to the culture medium (PubMed=31476588).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3495; ETV6 (Note=ETV6-RUNX1 fusion).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:10471; RUNX1 (Note=ETV6-RUNX1 fusion).
Genetic integration: Method=Transfection; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)).
Genetic integration: Method=Transfection; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR.
Genetic integration: Method=Transfection; Gene=UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (Note=With p.Met1_Arg360del).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_XI76 (IMSUTi002-A)
Sex of cell Male
Age at sampling Age unspecified
Category Induced pluripotent stem cell
Publications

PubMed=31476588; DOI=10.1016/j.scr.2019.101546
Takahashi M., Yamazaki S.
Generation of a human induced pluripotent stem cell line, IMSUTi002-A-1, harboring the leukemia-specific fusion gene ETV6-RUNX1.
Stem Cell Res. 40:101546-101546(2019)

Cross-references
Cell line databases/resources hPSCreg; IMSUTi002-A-1
SKIP; SKIP005549
Encyclopedic resources Wikidata; Q94317362
Entry history
Entry creation19-Dec-2019
Last entry update19-Dec-2024
Version number12