ID   IMSUTi002-A-1
AC   CVCL_XI77
SY   7F3955-ETV6-RUNX1; CRIEPIi003-A-1
DR   hPSCreg; IMSUTi002-A-1
DR   SKIP; SKIP005549
DR   Wikidata; Q94317362
RX   PubMed=31476588;
CC   From: Sustainable System Research Laboratory, Central Research Institute of Electric Power Industry (CRIEPI); Chiba; Japan.
CC   Population: Japanese.
CC   Characteristics: Transfected with a Tet-on system so as to induce the expression of a mCherry and the ETV6-RUNX fusion protein with the addition of doxycycline to the culture medium (PubMed=31476588).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 3495; ETV6 (Note=ETV6-RUNX1 fusion).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 10471; RUNX1 (Note=ETV6-RUNX1 fusion).
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (Note=With p.Met1_Arg360del).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_XI76 ! IMSUTi002-A
SX   Male
AG   Age unspecified
CA   Induced pluripotent stem cell
DT   Created: 19-12-19; Last updated: 10-09-24; Version: 11
//
RX   PubMed=31476588; DOI=10.1016/j.scr.2019.101546;
RA   Takahashi M., Yamazaki S.;
RT   "Generation of a human induced pluripotent stem cell line,
RT   IMSUTi002-A-1, harboring the leukemia-specific fusion gene
RT   ETV6-RUNX1.";
RL   Stem Cell Res. 40:101546-101546(2019).
//