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Cellosaurus TRMP PDGFRB-WT (CVCL_XG47)

[Text version]
Cell line name TRMP PDGFRB-WT
Synonyms TRMP PDGFR WT; ATWT
Accession CVCL_XG47
Resource Identification Initiative To cite this cell line use: TRMP PDGFRB-WT (RRID:CVCL_XG47)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:8804; PDGFRB.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Beagle; VBO=VBO_0200131.
Hierarchy Parent: CVCL_XG04 (TRMP)
Sex of cell Female
Age at sampling Age unspecified
Category Spontaneously immortalized cell line
Publications

PubMed=2550144; DOI=10.1016/0092-8674(89)90510-2
Kazlauskas A., Cooper J.A.
Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins.
Cell 58:1121-1133(1989)

PubMed=1314164; DOI=10.1002/j.1460-2075.1992.tb05182.x; PMCID=PMC556586
Kashishian A.S., Kazlauskas A., Cooper J.A.
Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo.
EMBO J. 11:1373-1382(1992)

PubMed=1375321; DOI=10.1128/mcb.12.6.2534-2544.1992; PMCID=PMC364446
Kazlauskas A., Kashishian A.S., Cooper J.A., Valius M.
GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit.
Mol. Cell. Biol. 12:2534-2544(1992)

PubMed=7691811; DOI=10.1016/S0021-9258(17)36874-6
Lechleider R.J., Sugimoto S., Bennett A.M., Kashishian A.S., Cooper J.A., Shoelson S.E., Walsh C.T., Neel B.G.
Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor.
J. Biol. Chem. 268:21478-21481(1993)

PubMed=8443409; DOI=10.1091/mbc.4.1.49; PMCID=PMC300899
Kashishian A.S., Cooper J.A.
Phosphorylation sites at the C-terminus of the platelet-derived growth factor receptor bind phospholipase C gamma 1.
Mol. Biol. Cell 4:49-57(1993)

Cross-references
Encyclopedic resources Wikidata; Q98133564
Entry history
Entry creation06-Sep-2019
Last entry update19-Dec-2024
Version number6