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Cellosaurus TRMP (CVCL_XG04)

[Text version]
Cell line name TRMP
Accession CVCL_XG04
Resource Identification Initiative To cite this cell line use: TRMP (RRID:CVCL_XG04)
Comments Characteristics: Does not express PDGFRs (PubMed=2550144).
Doubling time: 24 hours (PubMed=7669722).
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: Beagle; VBO=VBO_0200131.
Hierarchy Children:
CVCL_XG05 (4TG-11)CVCL_XG30 (TRMP PDGFRB-p.Arg634)CVCL_XG31 (TRMP PDGFRB-p.Gly751)
CVCL_XG32 (TRMP PDGFRB-p.Phe1009)CVCL_XG33 (TRMP PDGFRB-p.Phe1009-p.Phe1021)CVCL_XG34 (TRMP PDGFRB-p.Phe1021)
CVCL_XG35 (TRMP PDGFRB-p.Phe716)CVCL_XG36 (TRMP PDGFRB-p.Phe740)CVCL_XG37 (TRMP PDGFRB-p.Phe740-p.Phe751)
CVCL_XG38 (TRMP PDGFRB-p.Phe740-p.Phe751-p.Phe771)CVCL_XG39 (TRMP PDGFRB-p.Phe751)CVCL_XG40 (TRMP PDGFRB-p.Phe763)
CVCL_XG41 (TRMP PDGFRB-p.Phe771)CVCL_XG42 (TRMP PDGFRB-p.Phe775)CVCL_XG43 (TRMP PDGFRB-p.Phe778)
CVCL_XG44 (TRMP PDGFRB-p.Phe857)CVCL_XG45 (TRMP PDGFRB-p.Phe966)CVCL_XG46 (TRMP PDGFRB-p.Phe970)
CVCL_XG47 (TRMP PDGFRB-WT)
Sex of cell Female
Age at sampling Age unspecified
Category Spontaneously immortalized cell line
Publications

PubMed=3233532; DOI=10.1007/BF00119247
Turker M.S., Monnat R.J. Jr., Fukuchi K.-i., Johnston P.A., Ogburn C.E., Weller R.E., Park J.F., Martin G.M.
A novel class of unstable 6-thioguanine-resistant cells from dog and human kidneys.
Cell Biol. Toxicol. 4:211-223(1988)

PubMed=2550144; DOI=10.1016/0092-8674(89)90510-2
Kazlauskas A., Cooper J.A.
Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins.
Cell 58:1121-1133(1989)

PubMed=1688246; DOI=10.1097/00008571-199112000-00005
Turker M.S., Duffin K.Z., Smith A.C., Martin G.M., Martin A.W., DiMartino D.L., Kersey D.S.
Multidrug resistance phenotype associated with selection of an aminopterin resistant dog kidney cell line.
Pharmacogenetics 1:149-160(1991)

PubMed=1314164; DOI=10.1002/j.1460-2075.1992.tb05182.x; PMCID=PMC556586
Kashishian A.S., Kazlauskas A., Cooper J.A.
Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo.
EMBO J. 11:1373-1382(1992)

PubMed=1375321; DOI=10.1128/mcb.12.6.2534-2544.1992; PMCID=PMC364446
Kazlauskas A., Kashishian A.S., Cooper J.A., Valius M.
GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit.
Mol. Cell. Biol. 12:2534-2544(1992)

PubMed=8443409; DOI=10.1091/mbc.4.1.49; PMCID=PMC300899
Kashishian A.S., Cooper J.A.
Phosphorylation sites at the C-terminus of the platelet-derived growth factor receptor bind phospholipase C gamma 1.
Mol. Biol. Cell 4:49-57(1993)

PubMed=8069455; DOI=10.1007/BF02631450
Fukuchi K.-i., Hearn M.G., Deeb S.S., Smith A.C., Ngoc Thao D., Miyazaki J.-i., Bothwell M., Martin G.M.
Activity assays of nine heterogeneous promoters in neural and other cultured cells.
In Vitro Cell. Dev. Biol. Anim. 30:300-305(1994)

PubMed=7669722
Chen S.-C., Pelletier D.B., Ao P., Boynton A.L.
Connexin43 reverses the phenotype of transformed cells and alters their expression of cyclin/cyclin-dependent kinases.
Cell Growth Differ. 6:681-690(1995)

Cross-references
Encyclopedic resources Wikidata; Q98133543
Entry history
Entry creation06-Sep-2019
Last entry update19-Dec-2024
Version number7