Cellosaurus PC9-LeptoM (CVCL_XA20)
| Cell line name | PC9-LeptoM |
|---|---|
| Synonyms | PC9 LeptoM |
| Accession | CVCL_XA20 |
| Resource Identification Initiative | To cite this cell line use: PC9-LeptoM (RRID:CVCL_XA20) |
| Comments | Part of: Brain metastasis cell lines panel. Population: Chinese; Han and Japanese. Characteristics: Brain leptomeningeal space metastatic derivative of parental cell line. Established after 3 passages in nude mice from intracisternal injection, followed by one passage from intracardiac injection and obtained from mice bearing leptomeningeal metastases. Characteristics: Transfected with HSV1-TK/GFP/Fluc (TGL). Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; Q9QNF7; Human herpesvirus 1 TK. Omics: Transcriptome analysis by RNAseq. Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029. |
| Sequence variations |
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| Disease | Lung adenocarcinoma (NCIt: C3512) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_XA18 (PC9-TGL) |
| Sex of cell | Male |
| Age at sampling | 45Y |
| Category | Cancer cell line |
| Web pages | https://apps.cnio.es/app/BrainMetastasis/CellLines |
| Publications | PubMed=28283064; DOI=10.1016/j.cell.2017.02.025; PMCID=PMC5405733 |
| Cross-references | |
| Cell line databases/resources | cancercelllines; CVCL_XA20 |
| Encyclopedic resources | Wikidata; Q98128512 |
| Gene expression databases | GEO; GSM2194124
GEO; GSM2194125 |
| Entry history | |
| Entry creation | 06-Sep-2019 |
| Last entry update | 10-Sep-2024 |
| Version number | 10 |