Cellosaurus MEL-1 INSGFP/w NEUROD1(-/-) (CVCL_XA17)
| Cell line name | MEL-1 INSGFP/w NEUROD1(-/-) |
|---|---|
| Accession | CVCL_XA17 |
| Resource Identification Initiative | To cite this cell line use: MEL-1 INSGFP/w NEUROD1(-/-) (RRID:CVCL_XA17) |
| Comments | Characteristics: Using homologous recombination an EGFP reporter gene was introduced in the INS locus (PubMed=31519700). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:7762; NEUROD1. Genetic integration: Method=Homologous recombination; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_XA16 (MEL-1 INSGFP/w) |
| Sex of cell | Male |
| Age at sampling | Blastocyst stage |
| Category | Embryonic stem cell |
| Publications | PubMed=31519700; DOI=10.2337/db19-0117; PMCID=PMC6868472 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q95988516 |
| Entry history | |
| Entry creation | 06-Sep-2019 |
| Last entry update | 19-Dec-2024 |
| Version number | 6 |