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Cellosaurus AG05229 (CVCL_X835)

[Text version]
Cell line name AG05229
Synonyms AG05229B
Accession CVCL_X835
Resource Identification Initiative To cite this cell line use: AG05229 (RRID:CVCL_X835)
Comments Population: Japanese.
Omics: miRNA expression profiling.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Thigh, skin; UBERON=UBERON_0004262.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Werner syndrome (NCIt: C3447)
Werner syndrome (ORDO: Orphanet_902)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_EQ35 (iWS229)
Originate from same individual CVCL_X836 ! AG12799
CVCL_X837 ! AG12800
Sex of cell Male
Age at sampling 25Y
Category Finite cell line
Publications

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=10615119; DOI=10.1038/71630
Wyllie F.S., Jones C.J., Skinner J.W., Haughton M.F., Wallis C., Wynford-Thomas D., Faragher R.G.A., Kipling D.
Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts.
Nat. Genet. 24:16-17(2000)

PubMed=16339323; DOI=10.1093/gerona/60.11.1386
Davis T., Baird D.M., Haughton M.F., Jones C.J., Kipling D.
Prevention of accelerated cell aging in Werner syndrome using a p38 mitogen-activated protein kinase inhibitor.
J. Gerontol., A, Biol. Sci. Med. Sci. 60:1386-1393(2005)

PubMed=19966276; DOI=10.1093/nar/gkp1103; PMCID=PMC2831322
Johnson J.E., Cao K., Ryvkin P., Wang L.-S., Johnson F.B.
Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential.
Nucleic Acids Res. 38:1114-1122(2010)

PubMed=24749076; DOI=10.1016/j.stemcr.2014.02.006; PMCID=PMC3986587
Cheung H.-H., Liu X.-Z., Canterel-Thouennon L., Li L., Edmonson C., Rennert O.M.
Telomerase protects Werner syndrome lineage-specific stem cells from premature aging.
Stem Cell Reports 2:534-546(2014)

Cross-references
Cell line collections (Providers) Coriell; AG05229
Cell line databases/resources CLO; CLO_0035159
Encyclopedic resources Wikidata; Q54739808
Gene expression databases GEO; GSM476004
GEO; GSM1184268
GEO; GSM1184269
GEO; GSM1535460
GEO; GSM1535472
Entry history
Entry creation05-Sep-2014
Last entry update29-Jun-2023
Version number13