ID   AG05229
AC   CVCL_X835
SY   AG05229B
DR   CLO; CLO_0035159
DR   Coriell; AG05229
DR   GEO; GSM476004
DR   GEO; GSM1184268
DR   GEO; GSM1184269
DR   GEO; GSM1535460
DR   GEO; GSM1535472
DR   Wikidata; Q54739808
RX   CelloPub=CLPUB00597;
RX   PubMed=10615119;
RX   PubMed=16339323;
RX   PubMed=19966276;
RX   PubMed=24749076;
CC   Population: Japanese.
CC   Omics: miRNA expression profiling.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Thigh, skin; UBERON=UBERON_0004262.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C3447; Werner syndrome
DI   ORDO; Orphanet_902; Werner syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_X836 ! AG12799
OI   CVCL_X837 ! AG12800
SX   Male
AG   25Y
CA   Finite cell line
DT   Created: 05-09-14; Last updated: 29-06-23; Version: 13
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RX   CelloPub=CLPUB00597;
RG   National Institute on Aging;
RT   "1994 catalog of cell lines. NIA Aging Cell Repository.";
RL   (In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994).
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RX   PubMed=10615119; DOI=10.1038/71630;
RA   Wyllie F.S., Jones C.J., Skinner J.W., Haughton M.F., Wallis C.,
RA   Wynford-Thomas D., Faragher R.G.A., Kipling D.;
RT   "Telomerase prevents the accelerated cell ageing of Werner syndrome
RT   fibroblasts.";
RL   Nat. Genet. 24:16-17(2000).
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RX   PubMed=16339323; DOI=10.1093/gerona/60.11.1386;
RA   Davis T., Baird D.M., Haughton M.F., Jones C.J., Kipling D.;
RT   "Prevention of accelerated cell aging in Werner syndrome using a p38
RT   mitogen-activated protein kinase inhibitor.";
RL   J. Gerontol., A, Biol. Sci. Med. Sci. 60:1386-1393(2005).
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RX   PubMed=19966276; DOI=10.1093/nar/gkp1103; PMCID=PMC2831322;
RA   Johnson J.E., Cao K., Ryvkin P., Wang L.-S., Johnson F.B.;
RT   "Altered gene expression in the Werner and Bloom syndromes is
RT   associated with sequences having G-quadruplex forming potential.";
RL   Nucleic Acids Res. 38:1114-1122(2010).
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RX   PubMed=24749076; DOI=10.1016/j.stemcr.2014.02.006; PMCID=PMC3986587;
RA   Cheung H.-H., Liu X.-Z., Canterel-Thouennon L., Li L., Edmonson C.,
RA   Rennert O.M.;
RT   "Telomerase protects Werner syndrome lineage-specific stem cells from
RT   premature aging.";
RL   Stem Cell Reports 2:534-546(2014).
//