Cellosaurus Ramos-Blue KD-Myd (CVCL_X592)
| Cell line name | Ramos-Blue KD-Myd |
|---|---|
| Accession | CVCL_X592 |
| Resource Identification Initiative | To cite this cell line use: Ramos-Blue KD-Myd (RRID:CVCL_X592) |
| Comments | Population: Caucasian. Characteristics: MyD88-deficient. This cell line does not respond or respond weakly to the activation of receptors which signaling is dependent on MyD88, such as TLR7 and TLR9. However, they are still responsive to TLR3 which is MyD88-independent (InvivoGen). Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of a NF-KappaB/AP-1 promoter. Virology: EBV-negative. Knockout cell: Method=shRNA knockdown; HGNC; HGNC:7562; MYD88. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:439; ALPP. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Derived from site: In situ; Ascites; UBERON=UBERON_0007795. Cell type: B-cell; CL=CL_0000236. |
| Sequence variations |
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| Disease | Burkitt lymphoma (NCIt: C2912) Burkitt lymphoma (ORDO: Orphanet_543) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0597 (Ramos) |
| Sex of cell | Male |
| Age at sampling | 3Y |
| Category | Cancer cell line |
| Web pages | https://www.invivogen.com/ramos-blue-kdmyd |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54949203 |
| Entry history | |
| Entry creation | 05-Sep-2014 |
| Last entry update | 19-Dec-2024 |
| Version number | 22 |