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Cellosaurus Ramos-Blue (CVCL_X591)

[Text version]
Cell line name Ramos-Blue
Accession CVCL_X591
Resource Identification Initiative To cite this cell line use: Ramos-Blue (RRID:CVCL_X591)
Comments Population: Caucasian.
Characteristics: Can be used to study the NF-kappaB and AP-1 signaling pathways in B-lymphocytes and in particular the TLR3, TLR7, TLR9 and NOD1 signaling pathways (InvivoGen).
Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of a NF-KappaB/AP-1 promoter.
Virology: EBV-negative.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:439; ALPP.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile254Asp (c.760_761AT>GA); Zygosity=Homozygous (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0597 (Ramos)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
Web pages https://www.invivogen.com/ramos-blue-cell
Cross-references
Encyclopedic resources Wikidata; Q54949202
Entry history
Entry creation05-Sep-2014
Last entry update19-Dec-2024
Version number19