| Cell line name |
RCC52 |
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| Accession |
CVCL_X534 |
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| Resource Identification Initiative |
To cite this cell line use: RCC52 (RRID:CVCL_X534) |
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| Comments |
Population: Chinese.
Doubling time: 23.4 hours (PubMed=24222125).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113. |
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| Sequence variations |
- Mutation; HGNC; HGNC:914; B2M; Simple; p.Ala6Profs*1 (c.16delG); Zygosity=Heterozygous (PubMed=18704411).
- Mutation; HGNC; HGNC:914; B2M; Simple; p.Leu15Phefs*41 (c.43_44delCT); Zygosity=Heterozygous; Note=Total loss of HLA class 1 expression (PubMed=18704411).
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| HLA typing |
Source: PubMed=18704411
| Class I | | HLA-A | A*02,11 | | HLA-B | B*46,60(40) | | HLA-C | C*w01,w07 |
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| Disease |
Sarcomatoid renal cell carcinoma (NCIt: C27893)
Renal cell carcinoma (ORDO: Orphanet_217071) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Male |
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| Age at sampling |
55Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=18704411; DOI=10.1007/s00262-008-0565-7; PMCID=PMC2793116
Hsieh C.-H., Hsu Y.-J., Chang C.-C., Liu H.-C., Chuang K.-L., Chuang C.-K., Pang S.-T., Hasumi K., Ferrone S., Liao S.-K.
Total HLA class I loss in a sarcomatoid renal carcinoma cell line caused by the coexistence of distinct mutations in the two encoding beta2-microglobulin genes.
Cancer Immunol. Immunother. 58:395-408(2009) PubMed=24222125
Hsieh C.-H., Chen H.-C., Chang Y.-H., Pang S.-T., Kuo M.-L., Chuang C.-K., Liao S.-K.
Co-existence of epithelioid and fibroblastoid subsets in a sarcomatoid renal carcinoma cell line revealed by clonal studies.
Anticancer Res. 33:4875-4889(2013) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q54949468
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| Entry history |
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| Entry creation | 05-Sep-2014 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 13 |
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