Cellosaurus cell line 8716 (CVCL

Cellosaurus 8716 (CVCL_WZ10)

[Text version]

Cell line name

8716

Accession

CVCL_WZ10

Resource Identification Initiative

To cite this cell line use: 8716 (RRID:CVCL_WZ10)

Comments

Omics: Genome sequenced (low read coverage).
Omics: Transcriptome analysis by RNAseq.
Miscellaneous: Age at sampling from personal communication of Castillo-Tong, Dan Cacsire.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.

Sequence variations

Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Lys3326Ter (c.9976A>T) (10204A>T); ClinVar=VCV000038266; Zygosity=Unspecified (PubMed=31150822).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=31150822).

Disease

High grade ovarian serous adenocarcinoma (NCIt: C105555)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_WZ08 ! 17480
CVCL_WZ09 ! 8715

Sex of cell

Female

Age at sampling

63Y

Category

Cancer cell line

STR profile

Source(s): PubMed=31150822

Markers:

Amelogenin	X
CSF1PO	10
D1S1656	13,15.3
D2S1338	16,17
D3S1358	14
D5S818	11
D6S1043	11,17
D7S820	11
D8S1179	14,15
D12S391	17,23
D13S317	10
D16S539	11
D18S51	16,18
D19S433	13,14
D21S11	28
FGA	24
Penta D	13,14
Penta E	12
TH01	9
TPOX	8,11
vWA	17,19

Publications

PubMed=31150822; DOI=10.1016/j.canlet.2019.05.032
Kreuzinger C., von der Decken I., Wolf A., Gamperl M., Koller J., Karacs J., Pfaffinger S., Bartl T., Reinthaller A., Grimm C., Singer C.F., Braicu E.I., Cunnea P., Gourley C., Smeets D., Boeckx B., Lambrechts D., Perco P., Horvat R., Berns E.M.J.J., Castillo-Tong D.C.
Patient-derived cell line models revealed therapeutic targets and molecular mechanisms underlying disease progression of high grade serous ovarian cancer.
Cancer Lett. 459:1-12(2019)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_WZ10

Encyclopedic resources

Wikidata; Q93310423

Entry history

Entry creation

06-Sep-2019

Last entry update

19-Dec-2024

Version number