ID   8716
AC   CVCL_WZ10
DR   cancercelllines; CVCL_WZ10
DR   Wikidata; Q93310423
RX   PubMed=31150822;
CC   Sequence variation: Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Lys3326Ter (c.9976A>T) (10204A>T); ClinVar=VCV000038266; Zygosity=Unspecified (PubMed=31150822).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=31150822).
CC   Omics: Genome sequenced (low read coverage).
CC   Omics: Transcriptome analysis by RNAseq.
CC   Miscellaneous: Age at sampling from personal communication of Castillo-Tong, Dan Cacsire.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
ST   Source(s): PubMed=31150822
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D12S391: 17,23
ST   D13S317: 10
ST   D16S539: 11
ST   D18S51: 16,18
ST   D19S433: 13,14
ST   D1S1656: 13,15.3
ST   D21S11: 28
ST   D2S1338: 16,17
ST   D3S1358: 14
ST   D5S818: 11
ST   D6S1043: 11,17
ST   D7S820: 11
ST   D8S1179: 14,15
ST   FGA: 24
ST   Penta D: 13,14
ST   Penta E: 12
ST   TH01: 9
ST   TPOX: 8,11
ST   vWA: 17,19
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_WZ08 ! 17480
OI   CVCL_WZ09 ! 8715
SX   Female
AG   63Y
CA   Cancer cell line
DT   Created: 06-09-19; Last updated: 19-12-24; Version: 9
//
RX   PubMed=31150822; DOI=10.1016/j.canlet.2019.05.032;
RA   Kreuzinger C., von der Decken I., Wolf A., Gamperl M., Koller J.,
RA   Karacs J., Pfaffinger S., Bartl T., Reinthaller A., Grimm C.,
RA   Singer C.F., Braicu E.I., Cunnea P., Gourley C., Smeets D., Boeckx B.,
RA   Lambrechts D., Perco P., Horvat R., Berns E.M.J.J., Castillo-Tong D.C.;
RT   "Patient-derived cell line models revealed therapeutic targets and
RT   molecular mechanisms underlying disease progression of high grade
RT   serous ovarian cancer.";
RL   Cancer Lett. 459:1-12(2019).
//