Cellosaurus cell line 8713 (CVCL

Cellosaurus 8713 (CVCL_WZ04)

[Text version]

Cell line name

8713

Accession

CVCL_WZ04

Resource Identification Initiative

To cite this cell line use: 8713 (RRID:CVCL_WZ04)

Comments

Omics: Genomics; Whole genome sequencing; Low read coverage.
Omics: Transcriptomics; RNAseq.
Miscellaneous: Age at sampling and TP53 mutation cDNA coordinates from personal communication of Castillo-Tong, Dan Cacsire.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.

Sequence variations

Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Gln1138Leu (c.3413A>T); ClinVar=VCV000051458; Zygosity=Unspecified (PubMed=31150822).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro152Argfs*18 (c.455delC); ClinVar=VCV000634779; Zygosity=Unspecified (PubMed=31150822).

Disease

High grade ovarian serous adenocarcinoma (NCIt: C105555)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

75Y

Category

Cancer cell line

STR profile

Source(s): PubMed=31150822

Markers:

Amelogenin	X
CSF1PO	12
D1S1656	11,12
D2S1338	18,25
D3S1358	14,15
D5S818	12
D6S1043	11
D7S820	8,9
D8S1179	15,16
D12S391	20,22
D13S317	8,11
D16S539	12
D18S51	19
D19S433	13,15
D21S11	30
FGA	21
Penta D	9,11
Penta E	7
TH01	6,7
TPOX	9,11
vWA	18,19

Publications

PubMed=31150822; DOI=10.1016/j.canlet.2019.05.032
Kreuzinger C., von der Decken I., Wolf A., Gamperl M., Koller J., Karacs J., Pfaffinger S., Bartl T., Reinthaller A., Grimm C., Singer C.F., Braicu E.I., Cunnea P., Gourley C., Smeets D., Boeckx B., Lambrechts D., Perco P., Horvat R., Berns E.M.J.J., Castillo-Tong D.C.
Patient-derived cell line models revealed therapeutic targets and molecular mechanisms underlying disease progression of high grade serous ovarian cancer.
Cancer Lett. 459:1-12(2019)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_WZ04

Encyclopedic resources

Wikidata; Q93310416

Entry history

Entry creation

06-Sep-2019

Last entry update

10-Apr-2025

Version number