ID   8713
AC   CVCL_WZ04
DR   cancercelllines; CVCL_WZ04
DR   Wikidata; Q93310416
RX   PubMed=31150822;
CC   Sequence variation: Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Gln1138Leu (c.3413A>T); ClinVar=VCV000051458; Zygosity=Unspecified (PubMed=31150822).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro152Argfs*18 (c.455delC); ClinVar=VCV000634779; Zygosity=Unspecified (PubMed=31150822).
CC   Omics: Genome sequenced (low read coverage).
CC   Omics: Transcriptome analysis by RNAseq.
CC   Miscellaneous: Age at sampling and TP53 mutation cDNA coordinates from personal communication of Castillo-Tong, Dan Cacsire.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
ST   Source(s): PubMed=31150822
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D12S391: 20,22
ST   D13S317: 8,11
ST   D16S539: 12
ST   D18S51: 19
ST   D19S433: 13,15
ST   D1S1656: 11,12
ST   D21S11: 30
ST   D2S1338: 18,25
ST   D3S1358: 14,15
ST   D5S818: 12
ST   D6S1043: 11
ST   D7S820: 8,9
ST   D8S1179: 15,16
ST   FGA: 21
ST   Penta D: 9,11
ST   Penta E: 7
ST   TH01: 6,7
ST   TPOX: 9,11
ST   vWA: 18,19
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   75Y
CA   Cancer cell line
DT   Created: 06-09-19; Last updated: 19-12-24; Version: 10
//
RX   PubMed=31150822; DOI=10.1016/j.canlet.2019.05.032;
RA   Kreuzinger C., von der Decken I., Wolf A., Gamperl M., Koller J.,
RA   Karacs J., Pfaffinger S., Bartl T., Reinthaller A., Grimm C.,
RA   Singer C.F., Braicu E.I., Cunnea P., Gourley C., Smeets D., Boeckx B.,
RA   Lambrechts D., Perco P., Horvat R., Berns E.M.J.J., Castillo-Tong D.C.;
RT   "Patient-derived cell line models revealed therapeutic targets and
RT   molecular mechanisms underlying disease progression of high grade
RT   serous ovarian cancer.";
RL   Cancer Lett. 459:1-12(2019).
//