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Cellosaurus SW1990/GZ (CVCL_WS12)

[Text version]
Cell line name SW1990/GZ
Accession CVCL_WS12
Resource Identification Initiative To cite this cell line use: SW1990/GZ (RRID:CVCL_WS12)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_175901; Gemcitabine (Gemzar).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Mutation; HGNC; HGNC:27310; FLCN; Simple; p.Gln533Ter (c.1597C>T); ClinVar=VCV000096480; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro191del (c.569_571CTC[1]) (c.572_574delCTC); ClinVar=VCV000458551; Zygosity=Heterozygous (from parent cell line).
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1723 (SW1990)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=21054984; DOI=10.3760/cma.j.issn.0529-5815.2010.13.010
An Y., Yao J., Wei J.-S., Lu Z.-P., Cai H.-H., Dai C.-C., Qian Z.-Y., Xu Z.-K., Miao Y.
Establish a gemcitabine-resistant pancreatic cancer cell line SW1990/GZ and research the relationship between SW1990/GZ and pancreatic cancer stem cell.
Zhonghua Wai Ke Za Zhi 48:999-1003(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WS12
Encyclopedic resources Wikidata; Q98132932
Entry history
Entry creation05-Jul-2019
Last entry update19-Dec-2024
Version number8