ID   SW1990/GZ
AC   CVCL_WS12
DR   cancercelllines; CVCL_WS12
DR   Wikidata; Q98132932
RX   PubMed=21054984;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI:175901; Gemcitabine (Gemzar).
CC   Sequence variation: Mutation; HGNC; 27310; FLCN; Simple; p.Gln533Ter (c.1597C>T); ClinVar=VCV000096480; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Pro191del (c.569_571CTC[1]) (c.572_574delCTC); ClinVar=VCV000458551; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
DI   NCIt; C8294; Pancreatic adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1723 ! SW1990
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 05-07-19; Last updated: 05-10-23; Version: 7
//
RX   PubMed=21054984; DOI=10.3760/cma.j.issn.0529-5815.2010.13.010;
RA   An Y., Yao J., Wei J.-S., Lu Z.-P., Cai H.-H., Dai C.-C., Qian Z.-Y.,
RA   Xu Z.-K., Miao Y.;
RT   "Establish a gemcitabine-resistant pancreatic cancer cell line
RT   SW1990/GZ and research the relationship between SW1990/GZ and
RT   pancreatic cancer stem cell.";
RL   Zhonghua Wai Ke Za Zhi 48:999-1003(2010).
//