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Cellosaurus OCT-1 (CVCL_WN86)

[Text version]
Cell line name OCT-1
Synonyms Oct-1; Osteocalcin-T antigen clone #1
Accession CVCL_WN86
Resource Identification Initiative To cite this cell line use: OCT-1 (RRID:CVCL_WN86)
Comments Doubling time: 27.3 hours (CelloPub=CLPUB00625).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Bone, calvaria; UBERON=UBERON_0004339.
Cell type: Osteoblast; CL=CL_0000062.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: (C57BL/6J x BALB/cJ) F2 rat Bgla promoter T-Ag transgenic.
Originate from same individual CVCL_WN87 ! OCT-2
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

CLPUB00508
Chen D., Chen H., Feng J.Q., Windle J.J., Koop B.A., Harris M.A., Bonewald L.F., Boyce B.F., Wozney J.M., Mundy G.R., Harris S.E.
Osteoblastic cell lines derived from a transgenic mouse containing the osteocalcin promoter driving SV40 T-antigen.
Mol. Cell. Differ. 3:193-212(1995)

PubMed=9421234; DOI=10.1359/jbmr.1997.12.12.2014
Kato Y., Windle J.J., Koop B.A., Mundy G.R., Bonewald L.F.
Establishment of an osteocyte-like cell line, MLO-Y4.
J. Bone Miner. Res. 12:2014-2023(1997)

CLPUB00625
Lau P., Hellweg C.E., Kirchner S., Arenz A., Baumstark-Khan C., Horneck G.
Induction of DNA-strand breaks after X-irradiation in murine bone cells of various differentiation capacities.
(In conference) Abstracts of the 35th COSPAR scientific assembly; pp.1960-1960; Committee on Space Research; Paris; France (2004)

PubMed=16738320; DOI=10.1128/mcb.02120-05; PMCID=PMC1489126
Zhang K.-Q., Barragan-Adjemian C., Ye L., Kotha S., Dallas M., Lu Y.-B., Zhao S.-J., Harris M., Harris S.E., Feng J.Q., Bonewald L.F.
E11/gp38 selective expression in osteocytes: regulation by mechanical strain and role in dendrite elongation.
Mol. Cell. Biol. 26:4539-4552(2006)

PubMed=20232074; DOI=10.1007/s00411-010-0272-6
Lau P., Baumstark-Khan C., Hellweg C.E., Reitz G.
X-irradiation-induced cell cycle delay and DNA double-strand breaks in the murine osteoblastic cell line OCT-1.
Radiat. Environ. Biophys. 49:271-280(2010)

Cross-references
Encyclopedic resources Wikidata; Q98128327
Entry history
Entry creation05-Jul-2019
Last entry update29-Jun-2023
Version number6