Cellosaurus hCK (CVCL_WL43)
| Cell line name | hCK |
|---|---|
| Accession | CVCL_WL43 |
| Resource Identification Initiative | To cite this cell line use: hCK (RRID:CVCL_WL43) |
| Comments | Group: Vaccine production cell line. Characteristics: Expresses large amounts of alpha-2,6-sialoglycans and small amounts of alpha-2,3-sialoglycans. Virology: Will be useful for influenza virus research, particularly studies involving human A/H3N2 influenza viruses and possibly for vaccine production. Knockout cell: Method=CRISPR/Cas9; VGNC; 46850; ST3GAL1. Knockout cell: Method=CRISPR/Cas9; VGNC; 46851; ST3GAL2. Knockout cell: Method=CRISPR/Cas9; VGNC; 108234; ST3GAL3. Knockout cell: Method=CRISPR/Cas9; VGNC; 46852; ST3GAL4. Knockout cell: Method=CRISPR/Cas9; VGNC; 46853; ST3GAL5. Knockout cell: Method=CRISPR/Cas9; VGNC; 46854; ST3GAL6. Knockout cell: Method=CRISPR/Cas9; UniProtKB; F1Q495; ST3GAL2L. Genetic integration: Method=Transfection; Gene=HGNC; 10860; ST6GAL1. Genetic integration: Method=Transfection; Gene=UniProtKB; P0C2P0; Aspergillus terreus blasticidin-S deaminase (Bsd). Derived from site: In situ; Kidney; UBERON=UBERON_0002113. Cell type: Epithelial cell of kidney; CL=CL_0002518. |
| Species of origin | Canis lupus familiaris (Dog) (Canis familiaris)
(NCBI Taxonomy: 9615)
Breed/subspecies: Cocker Spaniel; VBO=VBO_0200372. |
| Hierarchy | Parent: CVCL_0422 (MDCK) |
| Sex of cell | Female |
| Age at sampling | Adult |
| Category | Spontaneously immortalized cell line |
| Publications | PubMed=31036910; DOI=10.1038/s41564-019-0433-6 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q93984530 |
| Entry history | |
| Entry creation | 24-May-2019 |
| Last entry update | 10-Sep-2024 |
| Version number | 10 |