• Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=15945100).
  
• Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gly13Arg (c.37G>C); ClinVar=VCV000013899; Zygosity=Unspecified (PubMed=23455323).
  

PubMed=10338330; DOI=10.1097/00008390-199902000-00003
Rizos H., Darmanian A.P., Indsto J.O., Shannon J.A., Kefford R.F., Mann G.J.
Multiple abnormalities of the p16INK4a-pRb regulatory pathway in cultured melanoma cells.
Melanoma Res. 9:10-19(1999)

PubMed=11595726
Becker T.M., Rizos H., Kefford R.F., Mann G.J.
Functional impairment of melanoma-associated p16(INK4a) mutants in melanoma cells despite retention of cyclin-dependent kinase 4 binding.
Clin. Cancer Res. 7:3282-3288(2001)

PubMed=15945100; DOI=10.1002/ijc.21265
Becker T.M., Ayub A.L., Kefford R.F., Mann G.J., Rizos H.
The melanoma-associated 24 base pair duplication in p16INK4a is functionally impaired.
Int. J. Cancer 117:569-573(2005)

PubMed=23455323; DOI=10.1038/onc.2013.45
Becker T.M., Boyd S.C., Mijatov B., Gowrishankar K., Snoyman S., Pupo G.M., Scolyer R.A., Mann G.J., Kefford R.F., Zhang X.-D., Rizos H.
Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor.
Oncogene 33:1158-1166(2014)