Cellosaurus cell line 136-2 (CVCL

Cross-references
Cell line name	136-2
Accession	CVCL_W281
Resource Identification Initiative	To cite this cell line use: 136-2 (RRID:CVCL_W281)
Comments	Derived from site: Metastatic; Not specified.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Arg (c.737T>G); ClinVar=VCV000127822; Zygosity=Unspecified (PubMed=10070891).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=3402430; DOI=10.1002/j.1460-2075.1988.tb02909.x; PMCID=PMC454430 Versteeg R., Noordermeer I.A., Kruse-Wolters M., Ruiter D.J., Schrier P.I. c-myc down-regulates class I HLA expression in human melanomas. EMBO J. 7:1023-1029(1988) PubMed=10070891; DOI=10.1038/sj.bjc.6690147; PMCID=PMC2362648 Zerp S.F., van Elsas A., Peltenburg L.T.C., Schrier P.I. p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis. Br. J. Cancer 79:921-926(1999)
Cell line databases/resources	cancercelllines; CVCL_W281
Encyclopedic resources	Wikidata; Q54581655
Polymorphism and mutation databases	Cosmic; 1418452 IARC_TP53; 10953
Entry history
Entry creation	16-Apr-2014
Last entry update	19-Dec-2024
Version number	11