ID   136-2
AC   CVCL_W281
DR   cancercelllines; CVCL_W281
DR   Cosmic; 1418452
DR   IARC_TP53; 10953
DR   Wikidata; Q54581655
RX   PubMed=3402430;
RX   PubMed=10070891;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Arg (c.737T>G); ClinVar=VCV000127822; Zygosity=Unspecified (PubMed=10070891).
CC   Derived from site: Metastatic; Not specified.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 19-12-24; Version: 11
//
RX   PubMed=3402430; DOI=10.1002/j.1460-2075.1988.tb02909.x; PMCID=PMC454430;
RA   Versteeg R., Noordermeer I.A., Kruse-Wolters M., Ruiter D.J.,
RA   Schrier P.I.;
RT   "c-myc down-regulates class I HLA expression in human melanomas.";
RL   EMBO J. 7:1023-1029(1988).
//
RX   PubMed=10070891; DOI=10.1038/sj.bjc.6690147; PMCID=PMC2362648;
RA   Zerp S.F., van Elsas A., Peltenburg L.T.C., Schrier P.I.;
RT   "p53 mutations in human cutaneous melanoma correlate with sun exposure
RT   but are not always involved in melanomagenesis.";
RL   Br. J. Cancer 79:921-926(1999).
//