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Cellosaurus SHIN-3/PTEN (CVCL_W128)

[Text version]
Cell line name SHIN-3/PTEN
Accession CVCL_W128
Resource Identification Initiative To cite this cell line use: SHIN-3/PTEN (RRID:CVCL_W128)
Comments Population: Japanese.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:9588; PTEN.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Unspecified (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A670 (SHIN-3)
Sex of cell Female
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=18347155; DOI=10.1158/1535-7163.MCT-06-0724
Takei Y., Saga Y., Mizukami H., Takayama T., Ohwada M., Ozawa K., Suzuki M.
Overexpression of PTEN in ovarian cancer cells suppresses i.p dissemination and extends survival in mice.
Mol. Cancer Ther. 7:704-711(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_W128
Encyclopedic resources Wikidata; Q54953344
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number13