• Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=8980248).
  
• Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Unspecified (PubMed=8980248).
  

CLPUB00115
Kiyozuka Y., Noda T., Maruyama M., Adachi S., Ichijo M., Maeda H., Moriyama I., Imai S.
Establishment and characterization of CA125 and TPA producing human ovarian serous cystadenocarcinoma cell line (SHIN-3).
Hum. Cell 1:334-335(1988)

DOI=10.5795/jjscc.27.926
Kiyozuka Y., Imai S., Noda T., Morimoto J., Moriyama I., Ichijo M., Tsubura Y.
Establishment and characterization of human ovarian serous cystadenocarcinoma cell line (SHIN-3) which produces CA 125 and TPA in vitro.
Nihon Rinsho Saibo Gakkai Zasshi 27:926-935(1988)

PubMed=2469292; DOI=10.1111/j.1440-1827.1989.tb02401.x
Imai S., Maeda H., Kiyozuka Y., Noda T., Moriyama I., Ichijo M.
Characterization of the CA125 antigen secreted from a newly established human ovarian cancer cell line (SHIN-3).
Acta Pathol. Jpn. 39:43-49(1989)

PubMed=2314830; DOI=10.1159/000226813
Imai S., Kiyozuka Y., Maeda H., Noda T., Hosick H.L.
Establishment and characterization of a human ovarian serous cystadenocarcinoma cell line that produces the tumor markers CA-125 and tissue polypeptide antigen.
Oncology 47:177-184(1990)

PubMed=8718548
Murakami F.
Cytotoxic action of monoclonal antibodies OC125 and SH-9 on ovarian cancer cell lines.
Nihon Sanka Fujinka Gakkai Zasshi 48:125-132(1996)

PubMed=8980248; DOI=10.1002/(SICI)1097-0215(19961220)69:6<466::AID-IJC8>3.0.CO;2-2
Ichikawa Y., Yoshida S., Koyama Y., Hirai M., Ishikawa T., Nishida M., Tsunoda H., Kubo T., Miwa M., Uchida K.
Inactivation of p16/CDKN2 and p15/MTS2 genes in different histological types and clinical stages of primary ovarian tumors.
Int. J. Cancer 69:466-470(1996)

PubMed=15677628; DOI=10.1093/carcin/bgi032
Gorringe K.L., Chin S.-F., Pharoah P.D.P., Staines J.M., Oliveira C., Edwards P.A.W., Caldas C.
Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer.
Carcinogenesis 26:923-930(2005)