Cellosaurus cell line Q34 (CVCL

Cross-references
Cell line name	Q34
Accession	CVCL_VS16
Resource Identification Initiative	To cite this cell line use: Q34 (RRID:CVCL_VS16)
Comments	Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Met53Thr (c.158T>C); ClinVar=VCV001480737; Zygosity=Heterozygous (PubMed=12417717). Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Asp108Asn (c.322G>A) (p.Arg122Gln, c.365G>A); ClinVar=VCV000216275; Zygosity=Heterozygous (PubMed=12417717).
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_VS15 ! Hmel-p16-2
Sex of cell	Female
Age at sampling	28Y
Category	Finite cell line
Publications	PubMed=12417717; DOI=10.1128/mcb.22.23.8135-8143.2002; PMCID=PMC134058 Huot T.J., Rowe J., Harland M., Drayton S., Brookes S., Gooptu C., Purkis P., Fried M., Bataille V., Hara E., Newton-Bishop J.A., Peters G. Biallelic mutations in p16(INK4a) confer resistance to Ras- and Ets-induced senescence in human diploid fibroblasts. Mol. Cell. Biol. 22:8135-8143(2002)
Encyclopedic resources	Wikidata; Q98128734
Entry history
Entry creation	25-Feb-2019
Last entry update	19-Dec-2024
Version number	9