Cellosaurus cell line MDA-PATC43 (CVCL

Cellosaurus MDA-PATC43 (CVCL_VR70)

Cross-references
Cell line name	MDA-PATC43
Accession	CVCL_VR70
Resource Identification Initiative	To cite this cell line use: MDA-PATC43 (RRID:CVCL_VR70)
Comments	Characteristics: Established from a xenograft established in NOD/SCID mice. Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations	Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (PubMed=25485535). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Arg (c.34G>C); ClinVar=VCV000012579; Zygosity=Unspecified (PubMed=25485535).
Disease	Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	71Y
Category	Cancer cell line
Publications	PubMed=25336691; DOI=10.1158/1078-0432.CCR-14-0970; PMCID=PMC4268437 Li X.-Q., Truty M.J., Kang Y., Chopin-Laly X., Zhang R., Roife D., Chatterjee D., Lin E., Thomas R.M., Wang H.-M., Katz M.H.G., Fleming J.B. Extracellular lumican inhibits pancreatic cancer cell growth and is associated with prolonged survival after surgery. Clin. Cancer Res. 20:6529-6540(2014) PubMed=25485535; DOI=10.1038/labinvest.2014.143; PMCID=PMC4670045 Kang Y., Zhang R., Suzuki R., Li S.-Q., Roife D., Truty M.J., Chatterjee D., Thomas R.M., Cardwell J., Wang Y., Wang H.-M., Katz M.H.G., Fleming J.B. Two-dimensional culture of human pancreatic adenocarcinoma cells results in an irreversible transition from epithelial to mesenchymal phenotype. Lab. Invest. 95:207-222(2015)
Cell line databases/resources	cancercelllines; CVCL_VR70
Encyclopedic resources	Wikidata; Q95987458
Entry history
Entry creation	25-Feb-2019
Last entry update	19-Dec-2024
Version number	9