ID   MDA-PATC43
AC   CVCL_VR70
DR   cancercelllines; CVCL_VR70
DR   Wikidata; Q95987458
RX   PubMed=25336691;
RX   PubMed=25485535;
CC   Characteristics: Established from a xenograft established in NOD/SCID mice.
CC   Sequence variation: Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (PubMed=25485535).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Arg (c.34G>C); ClinVar=VCV000012579; Zygosity=Unspecified (PubMed=25485535).
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
DI   NCIt; C9120; Pancreatic ductal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   71Y
CA   Cancer cell line
DT   Created: 25-02-19; Last updated: 19-12-24; Version: 9
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RX   PubMed=25336691; DOI=10.1158/1078-0432.CCR-14-0970; PMCID=PMC4268437;
RA   Li X.-Q., Truty M.J., Kang Y., Chopin-Laly X., Zhang R., Roife D.,
RA   Chatterjee D., Lin E., Thomas R.M., Wang H.-M., Katz M.H.G.,
RA   Fleming J.B.;
RT   "Extracellular lumican inhibits pancreatic cancer cell growth and is
RT   associated with prolonged survival after surgery.";
RL   Clin. Cancer Res. 20:6529-6540(2014).
//
RX   PubMed=25485535; DOI=10.1038/labinvest.2014.143; PMCID=PMC4670045;
RA   Kang Y., Zhang R., Suzuki R., Li S.-Q., Roife D., Truty M.J.,
RA   Chatterjee D., Thomas R.M., Cardwell J., Wang Y., Wang H.-M.,
RA   Katz M.H.G., Fleming J.B.;
RT   "Two-dimensional culture of human pancreatic adenocarcinoma cells
RT   results in an irreversible transition from epithelial to mesenchymal
RT   phenotype.";
RL   Lab. Invest. 95:207-222(2015).
//