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Cellosaurus TS/A-pc (CVCL_VQ63)

[Text version]
Cell line name TS/A-pc
Synonyms TSA-pc; TS/A p.c.; TS/A-parental cells
Accession CVCL_VQ63
Resource Identification Initiative To cite this cell line use: TS/A-pc (RRID:CVCL_VQ63)
Comments Caution: Termed "pc" for "parental cells" not because it is supposed to be identical to TS/A but because it is the parent cell line for a number of transfectants.
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Sequence variations
  • Mutation; MGI; MGI:98834; Trp53; Simple; p.Arg270His (c.809G>A); Zygosity=Unspecified (from parent cell line).
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/cAnNCrlBR.
Hierarchy Parent: CVCL_F736 (TS/A)
Sex of cell Female
Age at sampling 1Y8M
Category Cancer cell line
Publications

PubMed=7954438
Allione A., Consalvo M., Nanni P., Lollini P.-L., Cavallo F., Giovarelli M., Forni M., Gulino A., Colombo M.P., Dellabona P., Hock H., Blankenstein T., Rosenthal F.M., Gansbacher B., Bosco M.C., Musso T., Gusella L., Forni G.
Immunizing and curative potential of replicating and nonreplicating murine mammary adenocarcinoma cells engineered with interleukin (IL)-2, IL-4, IL-6, IL-7, IL-10, tumor necrosis factor alpha, granulocyte-macrophage colony-stimulating factor, and gamma-interferon gene or admixed with conventional adjuvants.
Cancer Res. 54:6022-6026(1994)

PubMed=7989764; DOI=10.4049/jimmunol.153.12.5659
Pericle F., Giovarelli M., Colombo M.P., Ferrari G., Musiani P., Modesti A., Cavallo F., Di Pierro F., Novelli F., Forni G.
An efficient Th2-type memory follows CD8+ lymphocyte-driven and eosinophil-mediated rejection of a spontaneous mouse mammary adenocarcinoma engineered to release IL-4.
J. Immunol. 153:5659-5673(1994)

PubMed=31783695; DOI=10.3390/cancers11121889; PMCID=PMC6966465
De Giovanni C., Nicoletti G., Landuzzi L., Palladini A., Lollini P.-L., Nanni P.
Bioprofiling TS/A murine mammary cancer for a functional precision experimental model.
Cancers (Basel) 11:1889.1-1889.20(2019)

Cross-references
Encyclopedic resources Wikidata; Q98133613
Entry history
Entry creation13-Nov-2018
Last entry update29-Jun-2023
Version number6