ID   TS/A-pc
AC   CVCL_VQ63
SY   TSA-pc; TS/A p.c.; TS/A-parental cells
DR   Wikidata; Q98133613
RX   PubMed=7954438;
RX   PubMed=7989764;
RX   PubMed=31783695;
CC   Sequence variation: Mutation; MGI; MGI:98834; Trp53; Simple; p.Arg270His (c.809G>A); Zygosity=Unspecified (from parent cell line).
CC   Caution: Termed "pc" for "parental cells" not because it is supposed to be identical to TS/A but because it is the parent cell line for a number of transfectants.
CC   Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
CC   Breed/subspecies: BALB/cAnNCrlBR.
DI   NCIt; C21678; Malignant neoplasms of the mouse mammary gland
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_F736 ! TS/A
SX   Female
AG   1Y8M
CA   Cancer cell line
DT   Created: 13-11-18; Last updated: 29-06-23; Version: 6
//
RX   PubMed=7954438;
RA   Allione A., Consalvo M., Nanni P., Lollini P.-L., Cavallo F.,
RA   Giovarelli M., Forni M., Gulino A., Colombo M.P., Dellabona P.,
RA   Hock H., Blankenstein T., Rosenthal F.M., Gansbacher B., Bosco M.C.,
RA   Musso T., Gusella L., Forni G.;
RT   "Immunizing and curative potential of replicating and nonreplicating
RT   murine mammary adenocarcinoma cells engineered with interleukin
RT   (IL)-2, IL-4, IL-6, IL-7, IL-10, tumor necrosis factor alpha,
RT   granulocyte-macrophage colony-stimulating factor, and gamma-interferon
RT   gene or admixed with conventional adjuvants.";
RL   Cancer Res. 54:6022-6026(1994).
//
RX   PubMed=7989764; DOI=10.4049/jimmunol.153.12.5659;
RA   Pericle F., Giovarelli M., Colombo M.P., Ferrari G., Musiani P.,
RA   Modesti A., Cavallo F., Di Pierro F., Novelli F., Forni G.;
RT   "An efficient Th2-type memory follows CD8+ lymphocyte-driven and
RT   eosinophil-mediated rejection of a spontaneous mouse mammary
RT   adenocarcinoma engineered to release IL-4.";
RL   J. Immunol. 153:5659-5673(1994).
//
RX   PubMed=31783695; DOI=10.3390/cancers11121889;
RA   De Giovanni C., Nicoletti G., Landuzzi L., Palladini A., Lollini P.-L.,
RA   Nanni P.;
RT   "Bioprofiling TS/A murine mammary cancer for a functional precision
RT   experimental model.";
RL   Cancers (Basel) 11:1889.1-1889.20(2019).
//