| Cell line name |
ELD-1 C-11 |
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| Synonyms |
ELD-1 subclone C-11 |
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| Accession |
CVCL_VN21 |
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| Resource Identification Initiative |
To cite this cell line use: ELD-1 C-11 (RRID:CVCL_VN21) |
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| Comments |
Problematic cell line: Contaminated. Ancestral cell line (MOBS-1) has been shown to be a U-937 derivative.
Population: Caucasian.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175. |
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| Sequence variations |
- Gene fusion; HGNC; HGNC:16063; MLLT10 + HGNC; HGNC:15514; PICALM; Name(s)=PICALM-MLLT10, CALM-AF10 (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gly129fs*51 (c.387_388insCGCC); Zygosity=Hemizygous (from parent cell line).
- Mutation; HGNC; HGNC:9644; PTPN11; Simple; p.Gly60Arg (c.178G>C); ClinVar=VCV000372590; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; c.559+1G>A (p.Val173Trpfs*59); ClinVar=VCV000428908; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
- Mutation; HGNC; HGNC:12796; WT1; Simple; p.Arg301Ter (c.901C>T) (p.Arg352Ter, c.1054C>T) (p.Arg374Ter, c.1120C>T); ClinVar=VCV000449416; Zygosity=Heterozygous (from parent cell line).
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| Disease |
Adult acute monocytic leukemia (NCIt: C8263)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_VN20 (ELD-1) |
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| Sex of cell |
Male |
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| Age at sampling |
37Y |
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| Category |
Cancer cell line |
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| Publications | DOI=10.14930/jsma1939.62.310
Tamaoki S., Iwamoto S., Ishida M., Sugisaki K., Nakamura K.
Roles of cytokines in interferon-gamma; generation by allogeneic response between CD8 T cells and a human dendritic cell-like cell line, ELD-1 -- a model of study for CD8 T cell promotion independent helper T cells.
Showa Igakkai Zasshi 62:310-320(2002) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_VN21
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| Encyclopedic resources |
Wikidata; Q93539953
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| Entry history |
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| Entry creation | 07-Sep-2018 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 11 |
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