Cell line name |
ORL-196 |
Synonyms |
ORL-196T; 196T |
Accession |
CVCL_VJ44 |
Resource Identification Initiative |
To cite this cell line use: ORL-196 (RRID:CVCL_VJ44) |
Comments |
Population: Indian. Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Oral cavity, buccal mucosa; UBERON=UBERON_0006956. |
Sequence variations |
- Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (PubMed=27050151).
- Mutation; HGNC; HGNC:3595; FAT1; Simple; p.Leu398Phefs*6 (c.1193dup); Zygosity=Unspecified (PubMed=27050151).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys321Asnfs*24 (c.960delG); Zygosity=Unspecified (PubMed=24224046; PubMed=27050151).
|
Disease |
Buccal mucosa squamous cell carcinoma (NCIt: C4040) Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Sex of cell |
Female |
Age at sampling |
59Y |
Category |
Cancer cell line |
STR profile |
Source(s): PubMed=27050151
Markers:Amelogenin | X |
CSF1PO | 10,12 |
D2S1338 | 22,23 |
D3S1358 | 14,17 |
D5S818 | 13,14 |
D7S820 | 8 |
D8S1179 | 13,15 |
D13S317 | 12 |
D16S539 | 12,13 |
D18S51 | 15 |
D19S433 | 14.2,16 |
D21S11 | 29,32.2 |
FGA | 21,22 |
TH01 | 6,7 |
TPOX | 8,11 |
vWA | 14,16 |
Run an STR similarity search on this cell line |
Publications | PubMed=24224046; DOI=10.1371/journal.pone.0080229; PMCID=PMC3817115 Zanaruddin S.N.S., Yee P.-S., Hor S.Y., Kong Y.H., Ghani W.M.N.W.A., Mustafa W.M.W., Zain R.B., Prime S.S., Rahman Z.A.A., Cheong S.-C. Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin. PLoS ONE 8:E80229-E80229(2013) PubMed=27050151; DOI=10.18632/oncotarget.8533; PMCID=PMC5053689 Fadlullah M.Z.H., Chiang I.K.-N., Dionne K.R., Yee P.-S., Gan C.P., Sam K.K., Tiong K.H., Ng A.K.W., Martin D., Lim K.P., Kallarakkal T.G., Mustafa W.M.W., Lau S.H., Abraham M.T., Zain R.B., Rahman Z.A.A., Molinolo A.A., Patel V., Gutkind J.S., Tan A.-C., Cheong S.-C. Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies. Oncotarget 7:27802-27818(2016) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_VJ44
|
Encyclopedic resources |
Wikidata; Q98128364
|
Polymorphism and mutation databases |
Cosmic; 2531646
Cosmic; 2559744
|
Entry history |
Entry creation | 07-Sep-2018 |
Last entry update | 19-Dec-2024 |
Version number | 9 |
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