ID   ORL-196
AC   CVCL_VJ44
SY   ORL-196T; 196T
DR   cancercelllines; CVCL_VJ44
DR   Cosmic; 2531646
DR   Cosmic; 2559744
DR   Wikidata; Q98128364
RX   PubMed=24224046;
RX   PubMed=27050151;
CC   Population: Indian.
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (PubMed=27050151).
CC   Sequence variation: Mutation; HGNC; HGNC:3595; FAT1; Simple; p.Leu398Phefs*6 (c.1193dup); Zygosity=Unspecified (PubMed=27050151).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys321Asnfs*24 (c.960delG); Zygosity=Unspecified (PubMed=24224046; PubMed=27050151).
CC   Omics: Transcriptome analysis by RNAseq.
CC   Derived from site: In situ; Oral cavity, buccal mucosa; UBERON=UBERON_0006956.
ST   Source(s): PubMed=27050151
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 12
ST   D16S539: 12,13
ST   D18S51: 15
ST   D19S433: 14.2,16
ST   D21S11: 29,32.2
ST   D2S1338: 22,23
ST   D3S1358: 14,17
ST   D5S818: 13,14
ST   D7S820: 8
ST   D8S1179: 13,15
ST   FGA: 21,22
ST   TH01: 6,7
ST   TPOX: 8,11
ST   vWA: 14,16
DI   NCIt; C4040; Buccal mucosa squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   59Y
CA   Cancer cell line
DT   Created: 07-09-18; Last updated: 19-12-24; Version: 9
//
RX   PubMed=24224046; DOI=10.1371/journal.pone.0080229; PMCID=PMC3817115;
RA   Zanaruddin S.N.S., Yee P.-S., Hor S.Y., Kong Y.H., Ghani W.M.N.W.A.,
RA   Mustafa W.M.W., Zain R.B., Prime S.S., Rahman Z.A.A., Cheong S.-C.;
RT   "Common oncogenic mutations are infrequent in oral squamous cell
RT   carcinoma of Asian origin.";
RL   PLoS ONE 8:E80229-E80229(2013).
//
RX   PubMed=27050151; DOI=10.18632/oncotarget.8533; PMCID=PMC5053689;
RA   Fadlullah M.Z.H., Chiang I.K.-N., Dionne K.R., Yee P.-S., Gan C.P.,
RA   Sam K.K., Tiong K.H., Ng A.K.W., Martin D., Lim K.P., Kallarakkal T.G.,
RA   Mustafa W.M.W., Lau S.H., Abraham M.T., Zain R.B., Rahman Z.A.A.,
RA   Molinolo A.A., Patel V., Gutkind J.S., Tan A.-C., Cheong S.-C.;
RT   "Genetically-defined novel oral squamous cell carcinoma cell lines for
RT   the development of molecular therapies.";
RL   Oncotarget 7:27802-27818(2016).
//