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Cellosaurus HiDEP-1 (CVCL_VI03)

[Text version]
Cell line name HiDEP-1
Synonyms Human iPS cell-Derived Erythroid Progenitor-1
Accession CVCL_VI03
Resource Identification Initiative To cite this cell line use: HiDEP-1 (RRID:CVCL_VI03)
Comments Population: Japanese.
Characteristics: After in vitro induction of differentiation, will produce enucleated red blood cells. Expresses embryonic and fetal hemoglobin.
Characteristics: Expression of the HPV16 E6 and E7 genes is induced by tetracycline (PubMed=23533656).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11556; TAL1.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Cell type: Erythroid progenitor cell; CL=CL_0000038.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_VI02 (HiPS-RIKEN-4A-TAL1)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=23533656; DOI=10.1371/journal.pone.0059890; PMCID=PMC3606290
Kurita R., Suda N., Sudo K., Miharada K., Hiroyama T., Miyoshi H., Tani K., Nakamura Y.
Establishment of immortalized human erythroid progenitor cell lines able to produce enucleated red blood cells.
PLoS ONE 8:E59890-E59890(2013)

Patent=US8975072
Nakamura Y., Kurita R.
Human erythroid progenitor cell line comprising HPV E6/E7 operably linked to an inducible promoter and method for producing human enucleated red blood cells.
Patent number US8975072, 10-Mar-2015

Cross-references
Cell line collections (Providers) RCB; RCB4554
Encyclopedic resources Wikidata; Q54889536
Entry history
Entry creation14-May-2018
Last entry update19-Dec-2024
Version number13