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Cellosaurus LNCaP-CS10 (CVCL_V260)

[Text version]
Cell line name LNCaP-CS10
Accession CVCL_V260
Resource Identification Initiative To cite this cell line use: LNCaP-CS10 (RRID:CVCL_V260)
Comments Population: Caucasian.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; 644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; 7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0395 (LNCaP)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=19902465; DOI=10.1002/pros.21079
Ishikura N., Kawata H., Nishimoto A., Nakamura R., Ishii N., Aoki Y.
Establishment and characterization of an androgen receptor-dependent, androgen-independent human prostate cancer cell line, LNCaP-CS10.
Prostate 70:457-466(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_V260
Encyclopedic resources Wikidata; Q54902836
Entry history
Entry creation16-Apr-2014
Last entry update05-Oct-2023
Version number14