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Cellosaurus BE(2)-C/ADR(5) (CVCL_V006)

[Text version]
Cell line name BE(2)-C/ADR(5)
Synonyms Be2-C/ADR5; Be2C/ADR5
Accession CVCL_V006
Resource Identification Initiative To cite this cell line use: BE(2)-C/ADR(5) (RRID:CVCL_V006)
Comments Population: Caucasian.
Characteristics: Intermediate type (I-type) (from parent cell line).
Characteristics: MYCN-amplified NBL cell line (from parent cell line).
Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene deletion; HGNC; 11998; TP53; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Cys135Phe (c.404G>T); ClinVar=VCV000376559; Zygosity=Heterozygous (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0529 (SK-N-BE(2)-C)
Sex of cell Male
Age at sampling 2Y2M
Category Cancer cell line
Publications

PubMed=8665486; DOI=10.1016/0304-3835(96)04250-4
Diccianni M.B., Chau L.S., Batova A., Vu T.Q., Yu A.L.-T.
The p16 and p18 tumor suppressor genes in neuroblastoma: implications for drug resistance.
Cancer Lett. 104:183-192(1996)

PubMed=15390183; DOI=10.1002/gcc.20096
Gebauer S., Yu A.L.-T., Omura-Minamisawa M., Batova A., Diccianni M.B.
Expression profiles and clinical relationships of ID2, CDKN1B, and CDKN2A in primary neuroblastoma.
Genes Chromosomes Cancer 41:297-308(2004)

Cross-references
Cell line databases/resources cancercelllines; CVCL_V006
Encyclopedic resources Wikidata; Q54795863
Polymorphism and mutation databases Cosmic; 922660
Entry history
Entry creation16-Apr-2014
Last entry update05-Oct-2023
Version number18