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Cellosaurus RCC6/VHL (CVCL_UY82)

[Text version]
Cell line name RCC6/VHL
Synonyms RCC6-pVHL
Accession CVCL_UY82
Resource Identification Initiative To cite this cell line use: RCC6/VHL (RRID:CVCL_UY82)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:12687; VHL.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; HGNC; HGNC:12687; VHL; Simple; p.Ser111Gly (c.331A>G); ClinVar=VCV000633016; Zygosity=Hemizygous (from parent cell line).
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Clear cell renal carcinoma (ORDO: Orphanet_319276)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E056 (RCC6 [France])
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=21258414; DOI=10.1038/onc.2010.638
Perier A., Fregni G., Wittnebel S., Gad S., Allard M., Gervois-Segain N., Escudier B.J., Azzarone B., Caignard A.
Mutations of the von Hippel-Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma.
Oncogene 30:2622-2632(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UY82
Encyclopedic resources Wikidata; Q98128864
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number9