ID   RCC6/VHL
AC   CVCL_UY82
SY   RCC6-pVHL
DR   cancercelllines; CVCL_UY82
DR   Wikidata; Q98128864
RX   PubMed=21258414;
CC   Sequence variation: Mutation; HGNC; 12687; VHL; Simple; p.Ser111Gly (c.331A>G); ClinVar=VCV000633016; Zygosity=Hemizygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; 12687; VHL.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_E056 ! RCC6 [France]
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 25-02-19; Last updated: 10-09-24; Version: 8
//
RX   PubMed=21258414; DOI=10.1038/onc.2010.638;
RA   Perier A., Fregni G., Wittnebel S., Gad S., Allard M.,
RA   Gervois-Segain N., Escudier B.J., Azzarone B., Caignard A.;
RT   "Mutations of the von Hippel-Lindau gene confer increased
RT   susceptibility to natural killer cells of clear-cell renal cell
RT   carcinoma.";
RL   Oncogene 30:2622-2632(2011).
//