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Cellosaurus MM253c1-3D (CVCL_UM70)

[Text version]
Cell line name MM253c1-3D
Accession CVCL_UM70
Resource Identification Initiative To cite this cell line use: MM253c1-3D (RRID:CVCL_UM70)
Comments Selected for resistance to: ChEBI; CHEBI_4305; Dacarbazine (DTIC; (5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide)).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
Disease Amelanotic melanoma (NCIt: C3802)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_UM66 (MM253c1)
Sex of cell Male
Age at sampling 46Y
Category Cancer cell line
Publications

PubMed=7060019
Parsons P.G., Smellie S.G., Morrison L.E., Hayward I.P.
Properties of human melanoma cells resistant to 5-(3',3'-dimethyl-1-triazeno)imidazole-4-carboxamide and other methylating agents.
Cancer Res. 42:1454-1461(1982)

PubMed=6534346; DOI=10.1038/icb.1984.57
Hayward I.P., Parsons P.G.
Epigenetic effects of the methylating agent 5-(3-methyl-1-triazeno) imidazole-4-carboxamide in human melanoma cells.
Aust. J. Exp. Biol. Med. Sci. 62:597-606(1984)

PubMed=6690060
Hayward I.P., Parsons P.G.
Comparison of virus reactivation, DNA base damage, and cell cycle effects in autologous human melanoma cells resistant to methylating agents.
Cancer Res. 44:55-58(1984)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UM70
Encyclopedic resources Wikidata; Q95990209
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number8