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Cellosaurus MM253c1 (CVCL_UM66)

[Text version]
Cell line name MM253c1
Synonyms MM253cl
Accession CVCL_UM66
Resource Identification Initiative To cite this cell line use: MM253c1 (RRID:CVCL_UM66)
Comments Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (from parent cell line).
Disease Amelanotic melanoma (NCIt: C3802)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2604 (MM253)
Children:
CVCL_UM69 (MM253c1-1G)CVCL_UM67 (MM253c1-1T)CVCL_UM70 (MM253c1-3D)
CVCL_UM68 (MM253c1-4CG)
Sex of cell Male
Age at sampling 46Y
Category Cancer cell line
Publications

PubMed=7060019
Parsons P.G., Smellie S.G., Morrison L.E., Hayward I.P.
Properties of human melanoma cells resistant to 5-(3',3'-dimethyl-1-triazeno)imidazole-4-carboxamide and other methylating agents.
Cancer Res. 42:1454-1461(1982)

PubMed=6534346; DOI=10.1038/icb.1984.57
Hayward I.P., Parsons P.G.
Epigenetic effects of the methylating agent 5-(3-methyl-1-triazeno) imidazole-4-carboxamide in human melanoma cells.
Aust. J. Exp. Biol. Med. Sci. 62:597-606(1984)

PubMed=6690060
Hayward I.P., Parsons P.G.
Comparison of virus reactivation, DNA base damage, and cell cycle effects in autologous human melanoma cells resistant to methylating agents.
Cancer Res. 44:55-58(1984)

PubMed=3756862
Maynard K., Parsons P.G.
Cross-sensitivity of methylating agents, hydroxyurea, and methotrexate in human tumor cells of the Mer- phenotype.
Cancer Res. 46:5009-5013(1986)

PubMed=3127479; DOI=10.1111/1523-1747.ep12461022
McEwan M., Parsons P.G., Moss D.J.
Monoclonal antibody against human tyrosinase and reactive with melanotic and amelanotic melanoma cells.
J. Invest. Dermatol. 90:515-519(1988)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UM66
Encyclopedic resources Wikidata; Q95990205
Entry history
Entry creation25-Feb-2019
Last entry update05-Oct-2023
Version number7