Cellosaurus cell line CUTO-2 (CVCL

Cross-references
Cell line name	CUTO-2
Synonyms	CUTO2; Colorado University Thoracic Oncology-2
Accession	CVCL_UJ34
Resource Identification Initiative	To cite this cell line use: CUTO-2 (RRID:CVCL_UJ34)
Comments	Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations	Gene fusion; HGNC; HGNC:10261; ROS1 + HGNC; HGNC:10661; SDC4; Name(s)=SDC4-ROS1 (PubMed=24349229).
Disease	Lung adenocarcinoma (NCIt: C3512)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	68Y
Category	Cancer cell line
Publications	PubMed=24349229; DOI=10.1371/journal.pone.0082236; PMCID=PMC3862576 Davies K.D., Mahale S., Astling D.P., Aisner D.L., Le A.T., Hinz T.K., Vaishnavi A., Bunn P.A. Jr., Heasley L.E., Tan A.-C., Camidge D.R., Varella-Garcia M., Doebele R.C. Resistance to ROS1 inhibition mediated by EGFR pathway activation in non-small cell lung cancer. PLoS ONE 8:e82236.1-e82236.13(2013) PubMed=30538120; DOI=10.1158/0008-5472.CAN-18-1492; PMCID=PMC6359944 Neel D.S., Allegakoen D.V., Olivas V., Mayekar M.K., Hemmati G., Chatterjee N., Blakely C.M., McCoach C.E., Rotow J.K., Le A.T., Karachaliou N., Rosell R., Riess J.W., Nichols R., Doebele R.C., Bivona T.G. Differential subcellular localization regulates oncogenic signaling by ROS1 kinase fusion proteins. Cancer Res. 79:546-556(2019)
Encyclopedic resources	Wikidata; Q93460568
Entry history
Entry creation	25-Feb-2019
Last entry update	19-Dec-2024
Version number	9