ID   CUTO-2
AC   CVCL_UJ34
SY   CUTO2; Colorado University Thoracic Oncology-2
DR   Wikidata; Q93460568
RX   PubMed=24349229;
RX   PubMed=30538120;
CC   Sequence variation: Gene fusion; HGNC; HGNC:10261; ROS1 + HGNC; HGNC:10661; SDC4; Name(s)=SDC4-ROS1 (PubMed=24349229).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   68Y
CA   Cancer cell line
DT   Created: 25-02-19; Last updated: 19-12-24; Version: 9
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RX   PubMed=24349229; DOI=10.1371/journal.pone.0082236; PMCID=PMC3862576;
RA   Davies K.D., Mahale S., Astling D.P., Aisner D.L., Le A.T., Hinz T.K.,
RA   Vaishnavi A., Bunn P.A. Jr., Heasley L.E., Tan A.-C., Camidge D.R.,
RA   Varella-Garcia M., Doebele R.C.;
RT   "Resistance to ROS1 inhibition mediated by EGFR pathway activation in
RT   non-small cell lung cancer.";
RL   PLoS ONE 8:E82236-E82236(2013).
//
RX   PubMed=30538120; DOI=10.1158/0008-5472.CAN-18-1492; PMCID=PMC6359944;
RA   Neel D.S., Allegakoen D.V., Olivas V., Mayekar M.K., Hemmati G.,
RA   Chatterjee N., Blakely C.M., McCoach C.E., Rotow J.K., Le A.T.,
RA   Karachaliou N., Rosell R., Riess J.W., Nichols R., Doebele R.C.,
RA   Bivona T.G.;
RT   "Differential subcellular localization regulates oncogenic signaling
RT   by ROS1 kinase fusion proteins.";
RL   Cancer Res. 79:546-556(2019).
//