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Cellosaurus AIP WT MEF (CVCL_UJ03)

[Text version]
Cell line name AIP WT MEF
Synonyms AIP Wild-type Fibroblasts
Accession CVCL_UJ03
Resource Identification Initiative To cite this cell line use: AIP WT MEF (RRID:CVCL_UJ03)
Comments Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:98834; Trp53 (Note=With p.Met1_Lys302del).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell Sex unspecified
Age at sampling 12FD
Category Transformed cell line
Publications

PubMed=19850893; DOI=10.2353/ajpath.2009.081131; PMCID=PMC2789606
Heliovaara E., Raitila A., Launonen V., Paetau A., Arola J., Lehtonen H., Sane T., Weil R.J., Vierimaa O., Salmela P., Tuppurainen K., Makinen M., Aaltonen L.A., Karhu A.
The expression of AIP-related molecules in elucidation of cellular pathways in pituitary adenomas.
Am. J. Pathol. 175:2501-2507(2009)

PubMed=24662816; DOI=10.1038/onc.2014.50
Tuominen I., Heliovaara E., Raitila A., Rautiainen M.-R.I., Mehine M., Katainen R., Donner I., Aittomaki V., Lehtonen H.J., Ahlsten M., Kivipelto L., Schalin-Jantti C., Arola J., Hautaniemi S., Karhu A.
AIP inactivation leads to pituitary tumorigenesis through defective Galphai-cAMP signaling.
Oncogene 34:1174-1184(2015)

Cross-references
Cell line collections (Providers) ATCC; CRL-3287
Encyclopedic resources Wikidata; Q93323929
Entry history
Entry creation25-Feb-2019
Last entry update10-Sep-2024
Version number8