ID   AIP WT MEF
AC   CVCL_UJ03
SY   AIP Wild-type Fibroblasts
DR   ATCC; CRL-3287
DR   Wikidata; Q93323929
RX   PubMed=19850893;
RX   PubMed=24662816;
CC   Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:98834; Trp53 (Note=With p.Met1_Lys302del).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   12FD
CA   Transformed cell line
DT   Created: 25-02-19; Last updated: 10-09-24; Version: 8
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RX   PubMed=19850893; DOI=10.2353/ajpath.2009.081131; PMCID=PMC2789606;
RA   Heliovaara E., Raitila A., Launonen V., Paetau A., Arola J.,
RA   Lehtonen H., Sane T., Weil R.J., Vierimaa O., Salmela P.,
RA   Tuppurainen K., Makinen M., Aaltonen L.A., Karhu A.;
RT   "The expression of AIP-related molecules in elucidation of cellular
RT   pathways in pituitary adenomas.";
RL   Am. J. Pathol. 175:2501-2507(2009).
//
RX   PubMed=24662816; DOI=10.1038/onc.2014.50;
RA   Tuominen I., Heliovaara E., Raitila A., Rautiainen M.-R.I., Mehine M.,
RA   Katainen R., Donner I., Aittomaki V., Lehtonen H.J., Ahlsten M.,
RA   Kivipelto L., Schalin-Jantti C., Arola J., Hautaniemi S., Karhu A.;
RT   "AIP inactivation leads to pituitary tumorigenesis through defective
RT   Galphai-cAMP signaling.";
RL   Oncogene 34:1174-1184(2015).
//