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Cellosaurus LM-MEL-42 (CVCL_UC48)

[Text version]
Cell line name LM-MEL-42
Synonyms LM-Mel-42; Ludwig Melbourne-MELanoma-42
Accession CVCL_UC48
Resource Identification Initiative To cite this cell line use: LM-MEL-42 (RRID:CVCL_UC48)
Comments Part of: Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Doubling time: ~38 hours (ATCC=CRL-3335).
Omics: miRNA expression profiling.
Omics: Transcriptome analysis by microarray.
Miscellaneous: STR profile from personal communication of Cardwell, Tracy.
Derived from site: Metastatic; Spleen; UBERON=UBERON_0002106.
Sequence variations
HLA typing Source: PubMed=23527996
Class I
HLA-AA*11:01,02:01
HLA-BB*55,27
HLA-CC*03
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3335; Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81810,12
D7S82010,11
D13S31711
D16S53912
D21S1129
TH016,9.3
TPOX8
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=19221743; DOI=10.1007/s00262-009-0672-0; PMCID=PMC11029848
Gedye C., Quirk J., Browning J., Svobodova S., John T., Sluka P., Dunbar P.R., Corbeil D., Cebon J.S., Davis I.D.
Cancer/testis antigens can be immunological targets in clonogenic CD133+ melanoma cells.
Cancer Immunol. Immunother. 58:1635-1646(2009)

PubMed=23527996; DOI=10.1111/pcmr.12097
Behren A., Anaka M., Lo P.-H., Vella L.J., Davis I.D., Catimel J., Cardwell T., Gedye C., Hudson C., Stan R., Cebon J.S.
The Ludwig Institute for Cancer Research Melbourne melanoma cell line panel.
Pigment Cell Melanoma Res. 26:597-600(2013)

PubMed=27852308; DOI=10.1186/s12943-016-0554-y; PMCID=PMC5112703
Andrews M.C., Cursons J., Hurley D.G., Anaka M., Cebon J.S., Behren A., Crampin E.J.
Systems analysis identifies miR-29b regulation of invasiveness in melanoma.
Mol. Cancer 15:72.1-72.20(2016)

Cross-references
Cell line collections (Providers) ATCC; CRL-3335
Cell line databases/resources cancercelllines; CVCL_UC48
Encyclopedic resources Wikidata; Q95982535
Gene expression databases ArrayExpress; E-MTAB-1496
GEO; GSM2371773
Entry history
Entry creation13-Nov-2018
Last entry update19-Dec-2024
Version number10